Reversal of renal allograft rejection with intravenous methylprednisolone “pulse” therapy
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چکیده
منابع مشابه
Reversal of renal allograft rejection with intravenous methylprednisolone "pulse" therapy.
REJECTION CONTINUES TO BE A MAJOR PROBLEM confronting the transplant recipient and his surgeon. Acute reject,ion of renal allografts is commonly treated by increasing the daily oral dose of corticosteraids. Multiple complications of this therapy, including gastrointestinal hemorrhage and increased susceptibility to infection, have been reported. Intermittent large-dose intravenous corticosteroi...
متن کاملComparison of high-dose intravenous methylprednisolone with low-dose oral prednisolone in acute renal allograft rejection in children.
Two corticosteroid regimens were compared in a randomised, prospective study of 48 consecutive acute rejection episodes occurring at least one month after transplantation in 22 children who had received renal allografts. The higher dose schedule (intravenous methylprednisolone 600 mg/m2 daily for three days) was no more effective than the lower (oral prednisolone 3 mg/kg daily for three days) i...
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ulcerative colitis is a mucosal-inflammatory disease that usually involves the rectum and extends proximally to involve all or part of the colon. medications for treatment include anti-inflammatory agents such as 5-asa compounds, systemic and topical corticosteroids and immunomodulators. a 33 year-old female and 52 year-old male both diagnosed with severe active ulcerative colitis who were resi...
متن کامل[Corneal allograft rejection: topical treatment vs. pulsed intravenous methylprednisolone - ten years' result].
PURPOSE To evaluate the efficacy of intravenous 500 mg methylprednisolone in addition to topical treatment with 1% prednisolone in the treatment of the first episode of corneal endothelial rejection in patients that were submitted to corneal allograft transplantation. METHODS Retrospective case-control study with 81 patients that presented the first episode of corneal endothelial rejection an...
متن کاملMechanisms of Renal Allograft Rejection
Rejection is the major cause of graft failure, and if the injury to the tubules and glomeruli is severe, the kidney may not recover. It is therefore important to diagnose acute rejection as soon as possible to institute prompt antirejection therapy. Generally, the success with which rejection can be reversed by immunosuppressive agents determines the chance of long-term success of the transplan...
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ژورنال
عنوان ژورنال: Journal of Surgical Research
سال: 1972
ISSN: 0022-4804
DOI: 10.1016/0022-4804(72)90110-2